Hi Alfred Guru,
Thanks for getting back to me so quickly. Yes I've rebooted but it still doesn't work. However, before clicking post in a hasty way I just tried to see if it would work again and realized that I set my hotkey to open Alfred with 3 of those 4 keys so it was getting stuck on that. I've since changed the hotkey to open Alfred and voilá it's working again. I can do my favorite screen shots now. Yippeee.
You make me feel like a guru, lol.
Not!
I'll leave that up to you guys.
Thanks.