Your Mac was asleep, you play something and wont play properly
You have clicks and glitches
Your interface stuck, after connecting it.
Something is not picked
and more.
Command "KILLAUDIO" will "reset" all audio drivers, which are automatically restarted after some seconds. It simply kills all drivers, easy but effective.
Your audio stuck in troubles. Try AudioKiller
in Share your Workflows
Posted
MacOS has sometimes troubles with audio.
Command "KILLAUDIO" will "reset" all audio drivers, which are automatically restarted after some seconds. It simply kills all drivers, easy but effective.
http://www.packal.org/workflow/audio-killer