I see that sometimes the shortcut CTRL+F2 "Move focus to menu bar" is not working and I have to cycle to every opened application to find in which one it works. When I find it, then it starts working again also for other apps. It seems the problem can be Alfred (v2.6 built 374).
I made this simple check that I repeated several times with different apps:
Quit All Apps, so only Finder is actually opened.
Press CTRL+F2... it works
Open a program with Alfred (i.e. Safari)
Press CTRL+F2 in Safari... NOT working
Quit All Apps to be sure only Finder is running
Open Safari using the icon in the Dock
Press CTRL+F2 in Safari... It's working
I'm using OS X 10.10.2.
Thanks